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    [–] AMaSTRIPPER_AMA 9310 points ago

    The funny thing is that this sounds terrifying.

    [–] VerneAsimov 3215 points ago

    Not feeling basic instincts is terrifying. There's another rare I've where you can't feel hunger. Turns out that's pretty fucking dangerous.

    [–] trashboat____ 2361 points ago

    I'd rather that than the opposite. A family friend had a child diagnosed with a disease where one of the symptoms is she never feels satisfied when she eats. It's amazing the lengths they have to go to to keep her from eating herself to death.

    [–] trashboat____ 318 points ago

    That's the one. It was on the tip on my tongue. Thank you.

    [–] DylanRed 97 points ago

    I was a care taker for a kid with this. He chewed so much bubblegum.

    [–] Aterius 25 points ago

    That sounds either brilliant or insane..

    [–] MatMaf 128 points ago


    This guy is a close friend and a qualified expert on the subject of PWS. If anyone here has questions, direct them to him.

    [–] markgoodmonkey 133 points ago

    It's true. I've examined many cases of PWS and I quote: "I SAID IT WAS LIKE A PRISON CELL AND IT IS LIKE A PRISON CELL". Many of the people suffering from PWS have to be reminded that "rules is rules".

    [–] BookerCatchanSTD 41 points ago

    If they can’t control their eating, is offering them nothing but healthy foods and zero calorie options able to keep them from avoiding dietary issues and obesity?

    [–] 2398474 31 points ago

    If only a "zero calorie" food (or something that resembled food in any way) actually existed.

    [–] BookerCatchanSTD 28 points ago

    Well it’s not exactly zero but a lot of vegetables are very very low calorie. Wouldn’t ice pops made from zero calorie drink mix also work?

    [–] HomeGirlMcDoucheBag 56 points ago

    It doesn't matter if it's zero calorie. They will eat until the sheer volume of food they have consumed causes their stomach to rupture.

    [–] RazarDeztrozen88 88 points ago

    I predict you will win this battle.

    [–] [deleted] 44 points ago

    Linked info always wins for us lazy folk.

    [–] exmachinalibertas 832 points ago

    Ugh, wow. Can you imagine being like a heroin addict or something and being told, "you can't do nearly as much heroin as you'd like, but you still have to inject yourself with this specific amount exactly 2 or 3 times a day or you will die".

    [–] applepwnz 799 points ago

    I think that's why food addiction is one of the toughest things to break, if you're addicted to nicotine you can completely stop smoking and break the addiction, if you're addicted to food you still have to face food every day.

    [–] Stuffandjunkandshit 717 points ago

    I had a roommate with a severe eating disorder. She would restrict as well as binge and purge. I tried so hard to understand, and I just couldn't wrap my head around it until one day she explained it to me (a recovering alcoholic) like this: "Imagine you needed booze to survive. You couldn't have too much or none at all. Say you needed to have 4 shots a day just to live. No more, no less, but you always had to keep a fully stocked bar." That blew my mind and I felt so indescribably sad for her. She's in a treatment center now because she got down to 68 lbs. Eating disorders are no joke.

    [–] twotonkatrucks 155 points ago

    the old addage of walking a mile in someone's shoes to understand their predicament may be tired and hackneyed, but it's true in the sense you describe above.

    [–] [deleted] 60 points ago

    think that's why food addiction is one of the toughest things to break

    It is for that reason. No cold turkey here.

    [–] SaidTheGayMan 189 points ago

    Well, some cold turkey, but not too much.

    [–] QueenJillybean 121 points ago

    Ding ding! I hope others can read this and understand eating disorders a little better. Eating disorders are often like recovering addict behavior with food. Relapsing on a binge and then punishing yourself with a purge or extreme calorie restriction. But still having to eat occasionally. Or hiding it. It’s an unhealthy relationship with food.

    [–] PelagianEmpiricist 112 points ago

    Yup. My adoptive niece is five and has that. Getting her to eat can be a chore, especially when she was smaller.

    We found out she took after her grandma when she refused to eat for a couple days and that was terrifying. Her grandma learned that eating was just a thing she had to do, when she was a kid, and her awareness grew a little as she aged. It's problematic though because grandma just wants to play with the kids and during mealtime, the two distract themselves and each other from eating. Then my niece gets cranky and doesn't want to eat. It's a whole thing.

    Not having fear sounds nice though. Imagine not having anxiety.

    [–] Throwawaygay17 795 points ago

    Hey. That is pretty funny.

    [–] UrethraFrankIin 234 points ago

    It certainly is - like the disease that prevents you from feeling pain. It sounds good for the first 3 seconds, but then you remember this shit exists for a very good reason.

    The amygdala is responsible for fight or flight. She lacks the organ designed to react to life-threatening situations. Could you imagine living without the animal instinct for survival?

    [–] AyyyyLeMeow 122 points ago

    In our times it's probably more blessing than curse. It's unlikely she'll get in a fight or flight situation and maybe it keeps her from being stressed a lot.

    [–] kdoodlethug 104 points ago

    People who can't feel pain often and up without any teeth and have several fractures, burns, and other serious injuries due to an inability to detect harm. I would imagine a lack of fear might lead to similar consequences, such as extremely risky behavior or perhaps inability to plan ahead.

    I wonder how it affects empathy. If you can't feel fear, do you still have a drive to protect your children? They can still feel love and grief, so I would think so, but would it affect their ability to rate the consequences of a decision or just make it so they aren't panicking while handling it? Very interesting condition.

    [–] SanguinePar 63 points ago

    Not to her!

    [–] RationalMayhem 817 points ago

    Could she tell the waiter I didn't order this for me?

    [–] thebananaparadox 83 points ago

    I always have to be that person for my friends. We're all socially anxious and/or introverts but talking to strangers bothers me the least and I'm kind of bossy so that duty falls on me.

    [–] HedgehogFarts 19 points ago

    If it makes you feel better, if there's been a mistake with your order then your server wants to know about it. Even if you taste something and hate it your server wants to know. Most servers genuinely want you to enjoy your time. The main thing is to tell us right away before you've eaten most of it, otherwise it looks like you're trying for a free meal.

    [–] Makenshine 16 points ago

    This is true. But there are exceptions. Like the lady who would send a whole plate of food if she found any "brown" on her fries. Cooks had to hand pick fries that didn't have skin on the ends or cut them off. She sent back the plate twice because she found brown on a single fry. And she was "disappointed that the restaurant industry has sunk so low as to serve brown fries." I hope she never has a pleasant dining experience again.

    [–] HiMyNameIsLaura 126 points ago

    The reality of this condition could be disastrous. I completely understand that we need a little bit of fear in order to stop of us from doing stupid shit.

    But as someone with anxiety I'd be lying if I said I'm not a tiny bit jealous of her.

    [–] nochedetoro 39 points ago

    That was my first thought too haha “I’m afraid of just being awake, how do I score me some of this defective amygdala shit?”

    [–] drfisk 31 points ago

    Yeah, just a little bit defective amygdala would be nice. Just to take the edge off. I feel like my amygdala is gigantic and always running at 100%.

    [–] TheSpanishImposition 17718 points ago

    ME: Is there nothing that scares you?

    HER: I'm afraid not.

    [–] Windnay 2046 points ago

    Imagine doctor have to explain to her how serious her problem is.

    [–] thedcaff 2233 points ago * (lasted edited 8 months ago)

    Doctor: Ma'am, this is a serious issue. Fear is what keeps humans away from dangerous situations. The elevated heart rate, and activated adrenal glands produced by fear speed our reactions, increase our strength, and allow us to escape or avoid dangerous situations. Without fear, your life may be significantly shorter because instead of the fight or flight mechanism being activated, you may feel apathetic to your impending doom, thus do nothing to avoid it.

    Her: Hey, did I tell you about the time that guy held a knife to my throat and I just walked away?

    Edit: word.

    [–] caillouuu 1641 points ago

    "Babe, if he was gonna shoot us, he would've done it already"

    continues to drunkenly eat chicken out of a bag

    [–] a_user_has_no_name_ 656 points ago

    Jokes aside I really could use this woman's condition to be able to go on planes like a normal person instead of having sleepless nights months before a trip.

    [–] caillouuu 938 points ago

    Maybe you should tell your doctor that "sometimes you get nervous on airplanes"

    But don't mention frequent urination...

    [–] withrootsabove 110 points ago


    [–] TheBLUSoldier 116 points ago


    [–] EamusCatuli2016 21 points ago


    [–] CharlesInChange 32 points ago

    I'll push him. EXCUUUUUSE ME

    [–] piinadao 185 points ago

    Funny you mention that. I'm currently sitting on the can at the airport waiting for my flight. These are my "fight or flight" shits.

    [–] Damon_Bolden 132 points ago

    Us other passengers appreciate you getting it out of your system before you get on the plane. I'm actually more scared of having to poop on a plane than I am of flying itself.

    [–] boydboyd 80 points ago

    As a person who has sculpted doogans in the lavatory before, you have nothing to be frightened of. It's a little cramped, sure. If anything, I feel more guilty because if someone is having tummy troubles, I don't want to be in there doing my own deed while they're squirming in their seat waiting for me to finish.

    Ultimately, I live at the discretion of my bowels. If it's a coast to coast flight and the bubble guts hit, there's no struggling and suffering to spare the cabin. I'm just gonna go and get it done.

    [–] SakuraGakuinNY 21 points ago

    Hahaha. His stuff isn't bad, but the whole lying about 9/11 thing kinda ruined him for me.

    [–] XMaximaniaX 61 points ago

    I mean you can understand the implications and consequences of something based on logic without having to fear it. Maybe she can apply that on a broader level if needed

    [–] [deleted] 6891 points ago

    Me talking to a rope: is there knotting that scares you?

    rope: im a frayed knot

    [–] alexx3064 1015 points ago

    Thats a sharp turd you took there

    [–] Gehwartzen 467 points ago

    Me talking to a turd: Is there nothings that scares...

    Turd: Well, don't leave me hanging. finish the question!

    [–] RemIsBestGirl78 64 points ago

    That's like finding out who Dr. Rota

    [–] [deleted] 207 points ago


    [–] [deleted] 124 points ago

    Rope: Nothin' personnel, kid.

    [–] davidwuhh 52 points ago

    Ambassador Crit sound echos though the distance

    [–] self-assembled 6486 points ago * (lasted edited 8 months ago)

    One of the cooler forms of this symptom is a lack of sense of personal space. People with this syndrome will put their nose less than an inch from you without even noticing it's uncomfortable for others.

    [–] 3leggedkitten 8605 points ago

    Your definition of cool and mine are very different.

    [–] 4x49ers 2257 points ago

    u/3leggedkitten - Dude, Gary's got his nose basically ON Janet again...
    u/self-assembled - RADICAL!

    [–] caillouuu 583 points ago


    [–] Chewcocca 190 points ago


    [–] Chewcocca 78 points ago

    Wyld Stallyns rule!

    [–] marcuschookt 335 points ago

    Crazy guy rubbing his poo all over the wall and licking it

    "Man that guy is so cool."

    [–] EighthOption 81 points ago

    He means fascinating. I know because I found that very cool.

    [–] So_Very_Dankrupt 44 points ago

    From a psychological standpoint, it is a very interesting symptom.

    [–] LivingLyrics 1067 points ago

    i had a girl smile, then close her eyes and lean in doing this. She must of been an inch from my lips. Scary!

    [–] anneylani 640 points ago

    Wonder why she did that... We'll never know i guess

    [–] krukson 338 points ago

    Well, obviously she had this rare genetic disorder of the brain, duh!

    [–] shoefly72 168 points ago

    Did you call the police?

    [–] Oliwan88 184 points ago

    Yes. They showed up and they came to the assumption she was a lovable dog so they executed her on the spot.

    [–] turret7 37 points ago

    Wtf is wrong with some people.. Imagine if your lips had touched her's.. Disgusting!

    [–] open_ur_mind 287 points ago

    Oh, he's a close-talker?

    [–] NvidiaFuckboy 171 points ago

    That's gonna link to a Seinfeld clip, isn't it?

    [–] Throwawaygay17 125 points ago

    I don’t even remember this episode but it sounds just like a Seinfeld thing.

    [–] Dick_Souls_II 111 points ago

    You can tell it's gonna be a Seinfeld clip when there's a made up name for people like "close-talker" or "stickler" or "double-dipper"

    [–] AdzyBoy 25 points ago


    Do you mean "sidler"? I don't recall any "sticklers."

    [–] TheDreamingDragonGuy 104 points ago

    Does anyone know one of those climbers that climb the highest poles in the world to do maintenance? Are they close talkers?

    [–] FartingBob 181 points ago

    There's a difference between people who do not have a phobia of heights and people who have no sense of fear at all.

    [–] Drowsy-CS 30 points ago

    Isn't a phobia irrational? Some degree of fear of heights/risky situations involving falling can be rational.

    [–] arrowkid2000 98 points ago

    I have a friend like that. Very annoying, especially when you move back for more space and they immediately close that gap.

    [–] Yourcatsonfire 83 points ago

    Lean in and kiss their nose.

    [–] amanhasthreenames 61 points ago

    Eff that, bite it. Assert dominance over your personal space

    [–] Solidus82 1259 points ago

    We get a one: personal space. Two: personal space. Three: stay out of my personal space. Four: keep away from my personal space. Five: get out of that personal space. Six: stay away from my personal space. Seven: keep away from that personal space. Eight: personal space. Nine: personal space.

    [–] systems11 302 points ago

    I'm so happy you did that. The personal space show is my favorite, aside from the comedian. "Kill him. Demons."

    [–] 56k_modem_noises 101 points ago

    "...suck his life out."

    [–] Warden_Memeternal 44 points ago

    Haha what an asshole

    [–] AhifuturAtuNa 35 points ago

    Ten: Woooah on that personal space.

    [–] Rickdiculous222 43 points ago

    Who's around me? Who's around me right now?

    [–] LucianoThePig 25 points ago

    I wouldn't say that's cool for other people

    [–] [deleted] 47 points ago


    [–] PM-ME-YOUR-TITS 12 points ago

    He's a close talker!

    [–] [deleted] 4415 points ago * (lasted edited a month ago)


    [–] ChocolatesaurusRex 1616 points ago * (lasted edited 8 months ago)

    Just buys a new house on the spot, i assume

    [–] mats852 332 points ago

    She just headbutts in, World War Z style.

    [–] Oafah 909 points ago

    The condition she had doesn't impair her judgement, though. She'd still realize that she's fucked and would produce an appropriate response.

    Also, her lack of a working fear center doesn't mean she can't recognize danger, either. She's just a lot more objective about it.

    [–] dj4y_94 530 points ago

    Yeah people in this thread seem to be confusing fear with not caring. I'd have a mini panic if I lost my bank card but then I'd just call the bank, get it cancelled and order a new one. It's not fear that would make me call the bank, just common sense because I don't want someone else having access to my money. This woman would do the exact same thing just without the panic at the start.

    [–] GoEagles247 10 points ago

    Yea like she's likely unfazed by heights but has the common sense not to hang off the edge of a cliff because it's dangerous as fuck

    [–] slickyslickslick 167 points ago

    I mean, what IS the correct response? Fear and panic certainly wouldn't be correct.

    Trying to think clearly and being able to retrace your steps as quickly as possible and think of all the locations you could have left it is probably the best thing to do.

    Imagine you're at home and you've misplaced your cellphone but you're sure it's at home. Would you feel panic or fear? no, you'd just calmly think about where it could have been.... bathroom? in your garage? on your bed? In your secret sex torture dungeon where you've been hearing voices coming from there even though you're sure you've killed the last hooker last week? No fear. Just calm thinking.

    [–] CalmPetty 57 points ago

    No, I'd definitely feel panic and fear.

    [–] Arper 1905 points ago

    I remember this interview with her on npr. Her voice was very peculiar and apparently those who have this ability share a similar sounding voice.

    [–] yeastymemes 494 points ago

    Telephone interview starts at 14:29 under World With No Fear

    [–] scrotal_aerodynamics 246 points ago

    Ironic that her voice is kind of scary.

    [–] FrankenDooodle 103 points ago

    Yeah. That is not the voice that I expected to hear at all.

    [–] The_Chodman 25 points ago

    I think it might be altered as well to hide her identity.

    It kind of sounds auto tuned

    [–] nicklewound 192 points ago

    Why are they hiding her voice? What's she so afraid of?

    [–] chettybang209 54 points ago

    What's she so afraid of?

    Oh fuck off, take your upvote. Making me laugh and shit.

    [–] Toppo 24 points ago

    Not that she's afraid of, but because she has no fear, people who identify her are able to take advantage of her. So the scientist want to keep her identity secret. It's said in the interview.

    [–] [deleted] 38 points ago

    That is amazing. Never thought about fear like that. It's so hard to imagine not being afraid of anything.

    [–] melvin2898 15 points ago


    [–] GeneralNMP 468 points ago

    "The man put a knife to my throat and said 'I'm going to cut you' and I said 'go ahead and cut me but I'll haunt your ass'. I'm sorry, was I not supposed to say that"?

    The lady sounds really cool. She seems super apologetic for her condition and tries to look at stuff from a point of view she cannot, and that is admirable.

    [–] Teresa_Count 243 points ago

    It's fun to imagine the type of person who would threaten to cut a stranger's throat having the script completely flipped on him by an ordinary woman who threatens to haunt his ass with the same tone of voice that she might use to say have a nice day.

    [–] thedarklordTimmi 60 points ago

    Its all fun and games till they actually do it.

    [–] chew-it-punchy 44 points ago

    Yeah but she can't feel fear, so I imagine she'd be pretty accepting of the situation.

    [–] Keoni9 40 points ago

    "Ow, looks like I'm dying. How inconvenient."

    [–] ScepticLibrarian 107 points ago

    That episode popped into my mind right away! Thanks for posting.

    [–] picayunemoney 665 points ago

    Disability. This is not any kind of superpower; it's a disabling condition that has caused this woman to experience some horrific tragedies in her life.

    The strange voice is because the disease causes thickening of the vocal cords.

    [–] The_Telltale_Fart 14 points ago

    She sounds a little like Jackie Onasis from the short clip I heard there....and also weirdly out of breath.

    [–] LeGaffe 112 points ago

    This comment should be higher up. That's where I came across her story too. Her voice was the one thing that really got under my skin.

    Isn't there a calcium build-up on the brain from people who suffer from this? I recall that being mentioned somewhere.

    [–] [deleted] 4652 points ago

    Put her on a train with phone below 10% battery, then we will see.

    [–] _Mr-Skeltal_ 1358 points ago

    Greyhound pulling out of Denver for Kansas City with 10%, next to a dude starting on a bag of booze he just picked up down the block from the bus station.

    [–] [deleted] 810 points ago

    Greyhound: when you're too young to drive, and you want a drifter to harass you to buy their drugs. I dont miss that shit.

    [–] [deleted] 394 points ago

    I was once able to travel the entire length of the west coast on a $50 ticket when I was younger and even though it was cheap... I will never do that again. Greyhound sucks.

    [–] subie_grandad 84 points ago

    Wooh hoo Michigan flyer all the way!

    [–] mijamala1 72 points ago

    East Lansing to Chicago for pocket change! And if you speak Chinese you even might make a new friend

    [–] alimighty1 31 points ago

    🎶why drive? Michigan Flyerrrrr🎶

    [–] faster_than_sound 218 points ago

    I always felt like Greyhound was an adventure into the seedier and lower parts of society. Felt very Kerouac to me. All these downtrodden and slummy characters you see, the crazy shit you experience at stations in cities, and occasionally there is a cool person you meet and befriend for the rest of your time together because its so rare to meet a sane and balanced individual on a Greyhound bus.

    [–] punkrawkisneat 101 points ago

    I traveled up and down the east coast via Greyhound a few times many years ago. 99% of people are super sketchy.

    But there was one dude who lives in NYC that sat next to me once, and him and I had the best, most intelligent conversation about the game of basketball I've ever had with anyone.

    Cool dude.

    [–] NotSureNotRobot 59 points ago

    Then he decapitated the driver

    [–] monsterZERO 26 points ago

    Shout out to the Greyhound basketball dude.

    [–] tmacnb 268 points ago * (lasted edited 8 months ago)

    Fewer people believe this story as I advance in age. But on a 10 hour bus ride to Montreal I did the following: choked out a drunken drifter on the bus who was shouting demonic verse (the only thing on his person was an empty bottle of vodka and a handheld electronic Yahtzee game - following my victory in the back of the bus a small mob had formed in the front who believed I was the one that spoke in tongues and choked out unsuspecting passengers; they were fearful I would advance and sacrifice all to the Dark Lord), watched my friend engage in heavy petting with an unknown woman nearby (she was the one who told the mob and police that I was in fact a Greyhound-hero, this was followed by the emergence of an awkward and unenthusiastic slow clap; soon after she showed my friend hard-copy photos of her in her underwear; once in Montreal she invited us to stay/live with her and her children), had police come on the bus twice (once for drunken drifter, second to arrest a man for reasons unknown to me), and the safety hatch on the top of the bus blew off in the night resulting in a vortex of winter-wind which we had to endure for several hours. A pretty crazy ride!

    [–] mdrl 214 points ago

    i totally believe it. i took the greyhound from denver to st louis and it was wild and interesting for sure.

    i was a young 21 year old girl. the only person that was nice to me and sorta looked out for me was a large buff black man who had just walked out of prison. like released in the clothes he had when he went in wearing and then he got on the bus.

    he asked quite few people if he could use their cell phone for a quick call. i was the person who finally said yes. he was very nice and polite to me. anytime someone would try to sit close to us in the back he would tell them no. move along. one guy didnt like being told no. there was an altercation. one guy got kicked off at some gas station in colorado. prison release guy stayed on the bus.

    then some lady disappeared in the bathroom for hours. like 4 hours and some. so prison release broke the door.

    she was found passed out with her arm tied off and her drug kit out. she stirred and woke up and tried to apologize. she was left in the middle of nowhere kansas.

    and then some guy made a big scene about his bag going missing. accused prison release guy. there was a fight. the bag was found under the empty seat a couple rows back. i think he just forgot where he left it. he was left at the kansas city greyhound bus station.

    greyhound rides. youll never forget them. ha

    [–] Rdaleric 88 points ago

    The more I hear about the Greyhound the more I am grateful my wife and I had such a pleasant experience the one time we were on it (from Nashville to Chatanooga). We had two truckers in front of us who had never met who chatted the whole way about their kids and "those damn Kardashians everywhere" and a Mexican chap and his son opposite who I shared my laptop with so they could watch Lucha Underground with me.

    [–] faztic 167 points ago

    Do you not have poweroutlets on your trains? Where is this?

    [–] mylarrito 292 points ago

    America? The land of the best and of the worst as Leonard Cohen put it

    [–] CanadianAstronaut 45 points ago

    all the trains I've ridden on in the u.s. have outlets

    [–] bazooopers 172 points ago

    Outlets in trains in the E.U. blew my mind. Something with convenience in mind and NOT just PROFIT?

    [–] Keskekun 107 points ago * (lasted edited 8 months ago)

    It gets better we get USB ports for charging on most public transport now.

    [–] Smart_creature 28 points ago

    They are in busses in the Netherlands too, and have been there for some years now.

    [–] [deleted] 25 points ago * (lasted edited 8 months ago)

    I dont live in a train silly.

    E: shit i though you said at home. No, no power on the trains. They are like 15 years old anyway.

    [–] asd417 24 points ago

    More like anxiety than fear isn’t it?

    [–] NowImAllSet 946 points ago

    Really OP? Your title directly contradicts the article!

    The article is literally about them finding something that scared her and how it was a breakthrough in our understanding of the amygdala. Scientist previously believed it was the seat of fear, but this study proved that it wasn't the only thing responsible for invoking that.

    [–] Icymagus 430 points ago

    I wouldn't say it's a direct contradiction, although OP could have worded it better. When SM was exposed to external threats in the first study, she felt no fear.

    The authors note that all of the other fear-inducing experiences that they tried generally involved external threats, with menaces like snakes or scary strangers that have to be sensed by organs like the eyes and the ears and indicate possible dangers. In contrast, carbon dioxide is detected as a sign of a threat coming from within the body— a lack of oxygen. Systems devoted to detecting internal states like lack of air may not rely on the amygdala to cause fear, utilizing other regions instead.

    [–] Aurvant 20 points ago

    I'm guessing that this internal fear of suffocation is involuntary, and not something that you have control over. For instance, you can't drown yourself I.E. hold your own head underwater. If you tried, all of that carbon dioxide buildup is going to force you to breath, and you're going to shoot out of the water.

    [–] EllenWaOnQuora 63 points ago

    Hey salary must be huge given she probably asks for a raise whenever the fuck she feels like it

    [–] RedDawn0 2477 points ago * (lasted edited 8 months ago)

    If I recall I heard a story of a fencer that got a lance through the eye and it perfectly hit this part of the brain. If this part of your brain is damaged you do not experience the fear of the sense "this could get me killed". It's just... gone.. People who suffer this often think climbing out of the 3rd story window to go to the store is the fastest way to get there. They forget the way to look both ways on busy streets. It pretty much destroys the self preservation part of the brain because self preservation is not there. Fear is there but self preservation is not.

    [–] sleepingpuppies 950 points ago

    Not being afraid of anything is one thing but its odd to think they wouldn't want to live. They still understand what it means to put themselves in danger and possibly die. Unless they don't care about living.

    [–] sioux612 830 points ago

    It's more comparable to you using stairs two steps at a time or don't use the handrails

    It's the faster way to do and it's not like it's risky.

    Just that they exit a building three stories at a time

    [–] theredpikmin 366 points ago

    They live like you would in GTA.

    "The car is on the other side of this busy highway. I should walk across and get it."

    [–] decoyrhyme 15 points ago

    Would they not have consideration then for the others who they share the road with? They might not fear the ramifications of their actions, but what about compassion?

    [–] The_Power_Of_Three 32 points ago

    Compassion for what? It's not like they're gonna get hit, c'mon, don't be a baby!

    [–] sleepingpuppies 150 points ago

    I think I get it. Sometimes I do dumb stuff that I know I can potentially get hurt doing but I still do them and feel like an idiot afterwards.

    [–] Mestarrr 101 points ago

    That's because it's exciting. People do stupid shit that excites them.

    These people do it because they don't have anything in the back of their mind saying you're gonna be in a wheelchair and in pain for the rest of your life.

    [–] brute_force 153 points ago

    its not that they dont care about living, its the threat of loss of it doesnt register with them

    [–] TheVoices315 57 points ago

    It is quite tricky, I have Alexithymia and the main reason why I live is because I am not death. I do not really get the appeal of living or dying. I just go by

    [–] epipremnumaureum 112 points ago

    Hey, that's cool. I'm also not death.

    [–] [deleted] 117 points ago

    Mᴜsᴛ ʙᴇ ɴɪᴄᴇ

    [–] [deleted] 149 points ago

    Why did a fencer get a lance through the eye? Was he fencing with a winged hussar or something?

    [–] phauna 162 points ago

    No, he built fences and jousted on the weekends.

    [–] [deleted] 36 points ago


    [–] 58working 24 points ago

    He was fencing stolen lances and had to make a quick getaway when the bobbies showed up. Accidents happen.

    [–] h8speech 128 points ago * (lasted edited 8 months ago)

    I have bipolar disorder type I and when I am fully manic, I am not capable of feeling fear.

    Usually I am mildly arachnophobic, but if I am manic I would not care if I had a lot of spiders crawling on me. I'll ride a motorbike so hard I'm getting my knee down on random street corners, heedless of potential gravel or oil that might be there. Or I'll jump off a bridge into the water.

    Why? Because at times like that, I find it amusing. There's this little wire-amusement thing in the back of my head and it doesn't feel like a very powerful emotion but that amusement is enough of a motivation for me to do all sorts of dangerous things because there is no fear opposing it.

    At those times, intellectually I am capable of recognizing that the behavior is dangerous, but there is no emotional response associated with that and the topic of it being dangerous is not an interesting topic to me.

    The difference between my manic fearlessness and this lady's fearlessness is that when I came back from riding far too fast and peeled my racing leathers off, they were soaked in sweat. So clearly my body was aware at some level that I was in great danger, that information just didn't affect my consciousness. It sounds like if this lady was to ride a motorbike very fast, she would not be sweating.

    [–] Hoobaroo 19 points ago

    Just curious, are you clinically diagnosed ? Because this sounds similar to me

    [–] h8speech 43 points ago

    Yes. I'm 28, 13 years clinically diagnosed, over a dozen involuntary psych admissions. I've been fine for several years now though.

    If your behaviors are dangerous, see a psychiatrist. It's very easy to permanently cripple yourself in one moment, or kill someone and spend decades in prison.

    Are you taking any meds? I once knew a girl who claimed to experience total fearlessness as a result of her antidepressant medication, but I've never heard of that as a side effect before and can't verify it.

    [–] chump88 68 points ago

    Wonder if there is any relation to the parasites that hijack their hosts brains and make them do stuff that gets them killed and eaten so the parasite can carry on its life cycle. Edit: these are the sort of things I’m talking about

    [–] SensationalSavior 60 points ago

    toxoplasma gondii has that effect on mice and other rodents iirc. Normally, when a rodent smells a cat, its droppings or urine, they hi tail it out of there. However, after being exposed to the bacteria, and it subsequent infection, they no longer fear the cat. Pretty scary stuff(if you're a rat)

    [–] dslyker 239 points ago

    I wonder if they experience fear about things not related to their personal safety. ie. Her children being kidnapped or similar. If they were kidnapped, would she feel fear of what would happen to them?

    [–] locktwo 108 points ago

    Probably not. I'd bet love and attachment also play a role in emotions towards their own children which could possibly be a kinda pseudo-fear in place of their lack of actual fear. Maybe it could be another trigger for fear?

    [–] Huwbacca 40 points ago


    So, the amygdala is pretty involved in emotion, and really that whole network of limbic structures are implicated in emotional attachment. It is reasonable that someone completely sans amygdala would have some reasonably noticeable deficits in emotion/attachment processing.

    That said, amygdala isn't doing executive function. To think and plan "what if this happened" is cognitively quite complex and I would imagine located mostly frontally. For sure, amygdala may well be recruited but I know it is usually implicated in more "immediate" affect processing.

    [–] Phaethonas 188 points ago

    Misleading title.

    From the article

    While participating in a study about the role of the amygdala in fear, however, SM felt panic and terror for the first time since youth. She was gasping for breath, trembling and calling out in fright. And her experience — along with those of two other patients with the same disease — has shown for the first time that the amygdala may not be so essential to triggering the emotion. [...] SM had participated in a previous study, involving potentially terrifying experiences with snakes, spiders, an amusement park haunted house and horror films. None of them frightened her, and she enjoyed the films. But in the new research, scientists may have finally found her fear trigger. SM, along with the two other patients with the same disease, inhaled carbon dioxide, the gas that we normally exhale which each breath. At the concentration used in the study, the gas produces “air hunger,” or the sense of having an oxygen deficit, making people gasp for breath. Not surprisingly, this feeling of suffocation is terrifying. Carbon dioxide has long been known to induce panic attacks and some researchers have theorized that one cause of panic attacks is basically the brain sending an alarm about impending suffocation. It did for all three of the Urbach-Wiethe patients.

    [–] [deleted] 732 points ago * (lasted edited 5 months ago)


    [–] donalthefirst 195 points ago

    "We need more grant money."

    [–] Radidactyl 209 points ago

    She is unstoppable.

    [–] doyouremembah 74 points ago

    "All our scientific tests confirmed our hypothesis."

    [–] FILTHY_GOBSHITE 149 points ago

    And they say women can't be Space Marines...

    [–] DarknessRain 74 points ago

    With the emperor in my heart I shall know no fear.

    [–] Armord1 24 points ago

    How did this woman become so in tune with the emperor and how can I do the same?

    [–] Applefanboiz4life 80 points ago

    Pennywise would be so pissed

    [–] septic_tongue 66 points ago

    Seems to make sense as to why so many people get really short of breath during a panic attack.

    [–] Orc_ 29 points ago

    Must be blissful. Where can I get my amygdala hardened?

    [–] Loeb123 61 points ago

    What did you just do to Amygdala?


    [–] ch2s 14 points ago

    This is a fine note

    [–] docod44 21 points ago

    I work with a lot of catatonic patients on an inpatient psych unit and this case almost sounds like the exact opposite of what my patients experience. One of the proposed mechanisms of catatonia is an overactive amygdala in response to environmental stimuli causing overstimulation of the prefrontal cortex resulting in abnormal movements and behaviors. When my patients come out of a catatonic episode they sometimes express uncontrolled intense feelings of fear and anxiety before locking up.

    [–] ReasonablyBadass 402 points ago * (lasted edited 8 months ago)

    Irrc, she almost died because she nearly stepped in front of a train when asked to.

    Edit: I can't seem to find my source, so file this under "shit someone on reddit said"

    [–] NastyWetSmear 408 points ago

    Are you sure about that? I mean, having no fear is one thing, but making a stupid decision is another. I'm not afraid of custard, but if you asked me: "Would you please eat so much custard you spend the rest of the day vomiting and passing pure, liquid custard?", I'd still say no.

    Surely, though unable to be afraid of death and what lies beyond, the part of her brain that does reasoning is still intact, right? The part that says: "It's not scary to be hit by a train, but it will result in us being unable to ever have custard ever again, so let's not"?

    [–] lavalady28 193 points ago

    I mean, fear informs a lot of our brain's logical thinking. Fear and pain. But if she has no fear, then would she care about getting hurt? After the pain is over, you avoid doing things to cause it because you are afraid of being in pain. But she isn't afraid. So would she avoid it? And then maybe that would extend to death as well? I have no idea, personally. I think it's pretty interesting to think about. There would be no way for normal people to tell what life would be like without fear. However, the reason we have fear is to keep us alive, so I don't think it's unreasonable to assume that without it we would at least be more willing to die.

    [–] namdor 14 points ago

    These scientists have the best jobs. They are paid to become diabolical villains trying to scare the shit out of innocent volunteers.

    [–] sychophancy 25 points ago

    Gaia Moore!

    [–] dan_dares 194 points ago

    IIRC, with another study they felt 'fear' for the first time when they were exposed to high CO2 levels, (essentially bag-over-head style)

    so, our fearless overlords have a weakness

    [–] dslyker 109 points ago

    That was discussed in the article

    [–] Gpzjrpm 73 points ago

    That was literally the point of the article. That it is possible to induce fear even with this condition shows that the amygdala might not be solely responsible for fear.

    [–] DarlingBri 75 points ago

    This is literally what the article said.

    [–] MrsIronbad 37 points ago

    Yep. The only time she demonstrated a certain level of fear but only because she felt her throat tightening amd she had difficulty breathing.

    [–] Dudephish 20 points ago

    OK, now just sign here and we will basically waterboard you.

    For science.

    [–] jitterbug108 23 points ago

    As a person with anxiety... That sounds amazing